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Ranolazine dihydrochloride
CAS No. 95635-56-6
Ranolazine dihydrochloride ( RS-43285 )
Catalog No. M16826 CAS No. 95635-56-6
An anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 40 | In Stock |
|
| 100MG | 56 | In Stock |
|
| 200MG | 87 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRanolazine dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAn anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models.
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DescriptionAn anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models; also inhibits cardiac sodium channel Nav1.5, shows antiarrhythmic, antiepileptic, and analgesic effects.Other Indication Approved
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SynonymsRS-43285
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorCalciumChannel;SodiumChannel
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number95635-56-6
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Formula Weight500.46
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Molecular FormulaC24H35Cl2N3O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCl.Cl.COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC2=C(C)C=CC=C2C)CC1
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Chemical Name1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, hydrochloride (1:2)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sokolov S, et al. Front Pharmacol. 2013 Jun 21;4:78.
2. Noble D, et al. Heart. 2006 Jul;92 Suppl 4:iv1-iv5.
3. Wang WQ, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):875-81.
2. Noble D, et al. Heart. 2006 Jul;92 Suppl 4:iv1-iv5.
3. Wang WQ, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):875-81.
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